The UK has reported 58 coronavirus deaths and 4,715 cases in the latest 24-hour period.
The number of deaths marks a fall from last Saturday, 20 March, when 96 were recorded. Cases have also fallen week-on-week, down from 5,587 reported last Saturday.
First vaccine doses administered across the UK are edging closer to 30 million with figure now standing at 29,727,435, with some 3,293,517 people having also had a second vaccine dose.
The figures come as Boris Johnson declared there is nothing to dissuade him that England should stick to its lockdown "roadmap to freedom".
Speaking to the virtual Conservative Party spring conference, Boris Johnson said he was looking forward to going to the barbers, for a pint in a pub and to "unlocking our economy and getting back to the life we love".
But he warned that while "we are in a different world from last spring" there was a need to be "honest about the difficulties ahead".
"Stay local" measures have now been lifted in Wales, meaning there are no travel restrictions within the country for the first time since December.
Six people from two households can also meet and exercise outdoors, with self-contained holiday accommodation allowed to reopen from Saturday.
The relaxation of lockdown rules in Wales does not apply to people living in England, Scotland and Northern Ireland – but this could create challenges in communities that border the country.
The prime minister also told the party conference there were still unanswered questions about the impact of a third coronavirus wave from Europe, as he said "bitter experience" had shown a wave like the one in Europe would hit the UK "three weeks later".
Countries across the continent are facing rising cases, with Germany tightening its border controls as Health Minister Jens Spahn called for another strict lockdown.
Meanwhile Spain is planning to use €50m (£43m) in EU funds to cut its working week to four days in a bid to prevent further coronavirus outbreaks.